I'm pretty handy with Reaper, Audacity, and Adobe Audition. Reaper is a powerful DAW and a deal at $60. Audacity is, to me, a decent program (opening a file is File > Open) with a lot of enthusiastic online support.
But since producing spoken-word radio segments is about 90% of my work, I use Audition most of the time because Audition's waveform display is better than Audacity's and Reaper's, and having a detailed waveform display is necessary for performing micro-surgery on spoken-word files to edit out false starts ("wait -- let me try that again"), "uhs" and "mouth noises" (pops and clicks from tongue and lips) and other vocal tics that can be distracting to the radio listener. By comparison, Reaper's and Audacity's waveform displays are both cartoonish but certainly fine for music recording and processing.
I use Reaper for multitrack recording of music events in conjunction with a couple of audio adapters (Focusrite 18i8, 6i6), and for post-production of those recordings. I could use Audition for that but Reaper uses fewer resources on my ancient Atom-powered netbook so I feel it's less likely to max out the processor.
Audacity doesn't get launched here very much because it doesn't offer anything that I don't get with Audition or Reaper.