Reaper has been my number one DAW for the past decade, switching from Adobe Audition. I admire the developers for packing so much power into such a tightly coded machine.
Recently I have been moving more towards another DAW, Studio One, as it has fewer distractions and is tightly integrated with my main interface (Studio 192) and controller (Faderport
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Reaper has been rock solid for me, both as a live recording interface and a studio editor. If it was the only DAW on earth I could keep on trucking, and not miss much from the other DAWS I use regularly (Studio One, Harrison Mixbuss 32C, Samplitude, AA).