I've run the 722 alone, 722+V3line, and 722+V3AES. I can live with the 722 alone for low profile situations, but the 722 alone is not as pleasing as the the 722 fronted by the V3 in either mode for my tastes. I'm favoring the 722+V3line over the 722+V3AES but narrowly. The 722 ADC seems a little smoother than the V3 ADC.
It's already been said but it's worth repeating, you have to do what your ears like best. For me, I'm most happy with the 722+V3line. I think the V2 would be a better value, but I keep the V3 because I can use it to offer a 16-bit patch.