Well, I still haven't figured out a lot of what can be done with SpectraLayers 11, but I just tried using the "unmix crowd noise" for the first time with excellent results.
I took a 14 second part of a recording where there was a lot of crowd chatter under the main vocals and ran it through UVR5. Took the vocal file from there and ran the unmix crowd noise in SL11, and it gave me a pretty much perfect separation between the singer and the background chatter. It also was very quick doing that, although again it was only 14 seconds. Then I exported the "Foreground" layer, and mixed it back with the instrumental audio file from UVR5.
I'm hoping I can use this method in the future instead of agonizingly trying to remove chatter from vocal sections using the spectral repair feature of iZotope RX.