I've not tried moleskin, but I would think a patch of it would be used to cover the body of the microphone, taping it to the surface (the skin) or covering the adhesive tape used to attach to the surface with the fuzzy side facing out for fabric to brush against, basically adhered on three sides with the microphone's capsule grid opening facing out of the uncovered side. Best for omni lavs, will be a lot more challenging to keep the rear vents of directional mics uncovered and the sound unaffected.
Putting it on the clothing would be more likely to block sound transmission to the microphone.
I use the DPA concealers in a similar way, made specifically for omni lav use under fabric, reducing fabric noise. They are a little smooth clear plastic device into which the microphone fits, which gets taped down. The fabric then slides across the surface of the smooth plastic instead of the microphone itself. I alternately use the DPA boundary mounts for this (a re-purposed application) as they have a flat smooth surface and lay very flat. In combination with that I'm selecting fabrics that are both sonic ally transparent and "quiet", making less rustling and brushing noise. On top of that is geometry- there are essentially two ways to go with managing unavoidable fabric contact - loose or tight. Loose enough that there minimal, manageable contact, or tight enough that the fabric stays in place and doesn't shift in relation to the microphone.
Hats and glasses are different yet the same basic ideas apply.
If handling noise is being transmitted to the microphone through the cable, it can help to make a small cable loop near the microphone that serves as strain relief.
Any actual bumping or touching of the microphone is going to make noise no matter what.. especially anything contacting or brushing against the less than smooth grid of the microphone - particularly if its a woven mesh grid. A lot of what the concealers do is just keep direct contact off of the grid and microphone body itself, reducing direct contact noise but not fully eliminating it. SPL masks most quieter handling noise, so preferable to move and readjust during the loud sections and be still with minimized movement during the quiet parts.