We have two 722s since they were new, and a MixPre10T and 10-II and have never had a problem with the Hirose connector, other than one factory adapter for a 722 with a poor wire prep job at the strain relief.
Replacing a Hirose in a MixPre10 would be trivial if you wanted to DIY and could find the part. It does stick out to the side and you cannot sit the 10 on it's back with the stock sled, but you would really have to abuse it to break it IMO.