Absolutely RX De-click the first line of defense!
I keep mine on the Random Click dropdown menu. I find for most of the recordings I've made, Frequency Skew at 0.0, Sensitivity at 6.5 and Click Widening at 1.7 seems to be a pretty useful setting. It gets rid of almost all or most of the claps.
Of course, there are some "thick" claps that are really tough to knock down. In that case I check the Click's Only box and adjust the sliders as a previous poster mentioned. This way I can hear when the De-Click starts to interfere with any music.
Once a song ends, there's usually lots of screaming and clapping. It's really bright yellow in the Spectrogram display setting I use. So after De-Click, I'll go in and "paint" over the brightest/loudest crowd noise and "Attenuate" with Spectral Repair. Usually it lowers the crowd enough so if listening with headphones, there's no blow the ears out loudness. Sometimes, it'll sound more like a dropout, but it's easy to go back one step and try again. I'll also paint across all the whistles at the top of the display.
BTW, if the recording was made at an outside show and there was wind noise, since I only have the Standard version of RX (without the De-Wind module), I can often knock down some of the wind which shows up as a batch of "spikes" at the very bottom of the Spectrogram display.