The amount of free space shouldn't be measured in GB.
Ideally you should leave about 20% of the total space of the drive free. This is to allow for the OS to defrag the drive as well as a buffer for bad sectors. If it is a backup drive and you won't be writing, erasing, and re-writing data you probably could leave a little less space since the OS won't really have to defrag the drive. For drives that you will be recycling data it is important to leave space for the OS to do it's thing when defraging. Doesn't matter if it's the OS drive or a drive dedicated to data storage.