I'm running it on macOS Monterey (12.0.1) Intel fwiw. No problems yet.
System Requirements
Operating Systems:
Mac: macOS Mojave (10.14.6) - macOS Big Sur (11.6)*
Windows: Windows 10
* Intel Macs or Apple Silicon Macs in Rosetta mode only.
Plugin Formats:
AU, AAX, VST2, VST3.
All plug-in formats are 64-bit only.
Supported Hosts:
Logic Pro, Pro Tools 2021, Live 11, Cubase 10.5-11, Nuendo 11, Studio One 5, Reaper 6, FL Studio 20, Audition CC, Premiere Pro CC.