the delta 66 should work fine, but i need to ask why you would be buying it over the audiophile 2496?
the delta 66 has 4 in/4out analog on a breakout box, and the s/pdif connections are on the pci card. i'm not sure why you would need the 4x4 i/o, unless you plan on using it for multitracking
i have the audiophile 2496, and think its great. both the a/p 2496 and the delta 66 use the same drivers