it would work, but i wouldn't recomend it. It would be easier to run all 4 mics into a mixer, then pan them right, and run the two mixes of mics into the ua-5. Other than that, i don't think i'd mess with it. One thing i'd like to try sometime, would be a 4 mic mix, having the 4 mics spread out onstage, mix accordingly. Would be cool, but havn't had the time nor strenth to try it. Good luck man.