I think that the failure of only one channel, and the other channel presumably being fine, indicates that the failure isn't the card or optical cable, because problems with those would result in problems with both channels (since the data is not transmitted in discrete channels in the card or cable). Therefore, I would think that the problem is in the XLR cables or in the XLR connectors (in the mics or the UA5), but hopefully someone more knowledgeable can chime in...