first of all, i would change that vista thing onto old chap XP. I dont know if vista has the official ASIO support at this stage, or any reasonable drivers to get decent audio quality whle using it. Judging by people's comments i doubt it.
I've got a friend who heard from a friend who heard from a friend (who's actually a MAC user), but he read a blog that said...
I've been using Vista on my laptop since last year with several audio apps and drivers and the news is not nearly so dire. XP is definitely a safer and more conservative bet. But there are definitely reasons to run Vista if you are so inclined.
ASIO works on Vista, but it depends on the driver. As is typical vendors vary. I've had good luck with Roland/Edirol and Line6. On the otherhand M-Audio is nowhere to be found.
Vista's new built-in HD audio is promising, but there's little if any support for it yet by applications.
My applications mostly work fine. For audio I'm mostly using Sony ACID/Vegas/Sound Forge, Ableton Live, Native Instruments. ACID and Vegas don't officially support Vista and the media database doesn't work, but otherwise things seem to work ok. The new Sound Forge supports Vista.
Most of these micro-recorders just show up like a hard drive to your system, and this works fine under Vista. Usually you are just copying files from (and sometimes to) the recorder just as if it were an external drive. I'm using my Korg MR-1 recorder with my Vista laptop. The MR-1 didn't officially support Vista until the 1.5 update, but it worked just fine before.
Here are some good reasources for using Vista for audio.
Windows Vista Musician's Resource Page (not just Cakewalk specific):
http://www.cakewalk.com/Vista/default.aspPeter Kirn's Create Digital Music has been covering the Vista audio scene all along. Lots of driver and performance tuning info there.
http://createdigitalmusic.com/tag/vista/