Primary on-axis will be directly in front of the four holes for the MEMS on the front of the unit. Assuming the device is lying flat on a table, directly above and below that probably won't make much difference, because the "height" of the MEMS and front face of the unit is small in that dimension. The potentially audible attenuation of highest frequencies will occur when the source is positioned off-axis over to either either side (where the additional MEMS are located) because the MEMS across the front form a longer line along that axis and the body of the unit is significantly wider in that dimension. ..and around the back of the unit.
Dunno if any of this will be audible or not. Just speculating based on the fundamental acoustics of a line arrangement of sensors and the geometry of the unit. It might like orienting miniature omnis in our use cases. I can hear the tiny bit of highest frequency attenuation off-axis when playing around with the DPA miniature omnis, but found long ago that in actual use recording musical performances their orientation doesn't really matter much.